Melasma cream prescription by dermatologist
*Average online dermatologist response time from July-September 2026: 18.6 hours
- Board-certified dermatologists
- No medication subscriptions
- Choice of generic or customized formulas
Medications often prescribed for melasma:

Table of Content:
How to consult an online dermatologist for melasma? | Treatment options | How to get a prescription? | How does Miiskin compare to other treatment services? | What is melasma? | Signs of melasma | Causes | What else can you do to treat melasma? | Meet the dermatologists | FAQ
Content last updated October 22nd, 2026.
How to consult an online dermatologist for melasma treatment?
Through Miiskin, you can connect with a board-certified dermatologist for personalized melasma treatment online. After evaluating your skin concern, your dermatologist can recommend an appropriate treatment plan, including prescription medications or a customized formula when clinically appropriate.

Submit your skin concern
Describe your skin concern, answer a brief questionnaire, and upload your photos.

Dermatologist review
A board-certified dermatologist licensed in your state reviews your information and photos.

Get your treatment plan
Receive your treatment plan. Choose delivery or pickup at your preferred pharmacy.
Melasma treatment options
Through Miiskin, you can ask your dermatologist to prescribe an FDA-approved medication or a customized formula tailored to your skin – whichever option you feel most comfortable with.
FDA-approved medications
You can choose an FDA-approved medication (brand-name or generic), which can be filled at any pharmacy nationwide. These medications have been reviewed by the FDA for safety, effectiveness, and quality, and are widely used in dermatology.
- Tri-Luma®(Triple combination cream)
- Tretinoin(Generic Retin-A®)
- Azelaic acid(Generic Finacea®)
- Tranexamic acid(Generic Lysteda®)
- Tazarotene(Generic Tazorac®)
Prescribed only if medically appropriate. Your dermatologist decides which medication fits your case.
Customized formulas
Customized prescription formulas combine multiple active ingredients into one product tailored to your needs. They’re prepared by our trusted partner, Foothills Pharmacy, and delivered to your door. Most formulas are $48.99 with delivery included.
- ✓Hydroquinone
- ✓Tretinoin
- ✓Kojic acid
- ✓Niacinamide
- ✓Azelaic acid
- ✓Tranexamic acid
- ✓Fluocinolone
- ✓Hydrocortisone
- ✓Vitamin C
Compounded medications are not reviewed by the FDA for safety or efficacy.
How to get a melasma cream prescription?
You can have a consultation via Miiskin with a dermatologist. First time consultation is $59-$79 and medication refill visits are $39-$49.
Where can I buy my melasma treatment cream?
The dermatologists on the Miiskin network can issue a prescription to any pharmacy in the country. If you want a personalized formula, choose Foothills as your preferred pharmacy.
How does Miiskin compare to other online melasma services?
Swipe to compare →
| Feature | Miiskin | Nurx | Musely | Curology |
|---|---|---|---|---|
| Provider type | Board-certified dermatologist | Physician, NP or PA | Board-certified dermatologist | Physician, NP or PA |
| Choose your own provider | Yes | No | No | No |
| FDA-approved medications | Yes | Yes | No** | No** |
| Customized / compounded formulas | Yes | Yes | Yes | Yes |
| Choice of pharmacy | Yes | No | No | No |
| Subscription required | No | Yes | Yes | Yes |
| Response time | ~24 to 48 hrs* | ~2 days | ~24 hrs | 2 to 3 days |
* On average, Miiskin dermatologists respond in less than a day.
** Melasma prescriptions from Musely and Curology are offered as compounded custom formulas only. Neither provides a standard FDA-approved generic option.
Comparison based on information published on each service’s website, October 2026.
What is melasma?
Melasma is a common skin condition marked by brown or gray-brown patches, usually on the face (forehead, cheeks, nose, upper lip, and chin). These irregular, symmetrical patches are caused by excess melanin production.
Key triggers include sun exposure, hormonal changes (like pregnancy or birth control use), and genetics. Often called “the mask of pregnancy,” melasma is especially common in women during hormonal shifts.
Though it can be stubborn, treatment typically involves prescription topicals like hydroquinone, tretinoin, or azelaic acid. Daily sun protection is essential for managing and preventing melasma.
Signs and symptoms of melasma

Dark patches on your skin
Melasma causes patches that are darker than your natural skin color.

Both sides of face
The dark patches are somehow symmetrical on both sides of your face.

Covers a large area
The melasma dark patches can cover a large area of your face.

Worsens in the sun
Melasma becomes more noticeable if you spend more time outdoors.

It is harmless
Melasma is harmless and it does not feel painful or itchy, it is just bothersome.

Related to hormones
Melasma may appear when you go through hormonal changes in your life.
Causes of melasma

Sun exposure

Hormonal changes

Genetic predisposition

Aging
What else can you do to get rid of melasma?
Addressing melasma effectively can be a complex process, however, a multifaceted approach that includes a prescription-strength melasma cream together with sun protection and in-office treatments can significantly improve your outcome.

Sun Protection
Use a sunscreen with SPF 50 all year round and reapply often when outdoors.

Chemical peels
Chemical peels remove the outer layer of the skin and get rid of excessive pigmentation.

Laser therapy
Fractional lasers or intense pulsed light therapies target and reduce the melanin accumulation.

Meet the board-certified dermatologists
Miiskin partners exclusively with independent, board-certified dermatologists who have helped more than 200,000 people through telehealth.
Get a clear overview of the dermatologists in the Miiskin network, including where they’re licensed to practice, their experience, specialties, typical response time, and number of telehealth consultations completed.

Dark spots, uneven tone or fine lines?
Discoloration and signs of aging can look similar but respond to different treatments. Brown patches on the cheeks, forehead or upper lip may be melasma. Dark marks left behind after a breakout are often post-inflammatory hyperpigmentation (PIH). Fine lines and rough texture are usually treated with anti-aging prescriptions. A board-certified dermatologist can review your photos and recommend the right approach. Browse all skin, hair and nail conditions treated online.

Evidence-based melasma treatment creams
Studies show that 72% of patients with melasma who used hydroquinone for 4 months saw an overall improvement2.
Studies show that 77% of patients applying hydroquinone, tretinoin and fluocinolone acetonide a were almost clear of dark spots by week 83.
Studies show that patients using azelaic acid over a 24-week treatment period significantly reduced the intensity of pigmentation.4.







Need a prescription for melasma?