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Table of Content:
What is tretinoin? | What is tretinoin used for? | Tretinoin brand names | How to get tretinoin? | Get the prescription | How does tretinoin work? | Benefits | Warnings and precautions | Side effects | The tretinoin purge | How to use tretinoin? | Tretinoin and other medications |Tretinoin prescription request faq
What is tretinoin?
Tretinoin (also known by its brand names Retin-A or Tretin-X) is a prescription-strength topical gel or cream widely used by dermatologists to treat acne, hyperpigmentation, wrinkles, and sun damage1.
Tretinoin works by accelerating the lifecycle of skin cells and boosting new collagen formation. It belongs to a family of synthetic and natural compounds called retinoids that are derived from Vitamin A2.
How can I get a tretinoin prescription?
Do you need a prescription to buy a tretinoin?
Yes. Tretinoin is a prescription medication which means you need to have a consultation with a healthcare professional and it cannot be purchased over-the-counter (OTC).
How can you get a prescription for tretinoin?
You can have a virtual, photo-based consultation with a healthcare provider via the Miiskin app, and if they deem it adequate, you can buy tretinoin at the pharmacy of your choice.
How to get a tretinoin prescription online?

Download the free Miiskin app

Request a prescription via a virtual photo-based consultation

Get tretinoin prescribed

Pick it up at the pharmacy of your choice
Process to get a tretinoin prescription
Through the Miiskin app, you get in touch with a healthcare provider using a photo-based virtual consultation. The doctor will review your case and if tretinoin is suitable for you, the doctor can write you a prescription for tretinoin cream and you can pick it up at the pharmacy of your choice.
Request a tretinoin prescription online
Receive a personalized treatment plan.
Start a photo-based virtual consultation with an independent dermatology provider via the Miiskin app.

Tretinoin Explained
How do tretinoin creams work?
Tretinoin stimulates cell renewal in the epidermis, enhancing the cell layer, reducing pigmentation, and normalizing sun-damaged cells4.
Tretinoin also works in the dermis promoting the production of collagen and elastin thickening the dermal layer and making the skin appear more plump5.
According to multiple research, tretinoin gels and creams are a safe and effective therapeutic modality for the long-term treatment of acne and photoaging.6 78
Benefits of Tretinoin

Reduces fine wrinkles

Reduces the appearance of dark spots9

It inhibits the formation of comedones10

Faster regeneration of sun-damaged skin cells

Improves skin texture
Warning and precautions when using tretinoin creams or gels
This medication should only be used under medical supervision and it is advised that women use effective contraception when using tretinoin.
Tretinoin is considered teratogenic, and therefore it cannot be used by women who want to become pregnant, are pregnant, or are breastfeeding because it may cause serious harm to the fetus13 14.
Tretinoin is likely to make your skin more sensitive to sunlight so you should apply sunscreen with SPF 50 factor every morning while using this product and reapply every two hours when outdoors.
Tretinoin may cause skin irritation when you first start using it, follow the precise instructions of your healthcare provider to minimize unwanted side effects.
Do not combine tretinoin with other acne or pigmentation medications, unless indicated by your doctor.
Side effects of tretinoin
- Redness
- Peeling
- Itching
- Burning/Stinging
- Dryness15
What is the tretinoin purge?
The tretinoin purge (also known as tretinoin uglies) is a very common skin reaction that occurs when a patient uses tretinoin for the first time.

How to start using prescribed tretinoin?
You should always follow the precise instructions of your healthcare provider, but as a general rule, if you have never used tretinoin, here is an excellent way to start.
- First 2 to 4 weeks:
Apply tretinoin .025% two nights per week in the evenings - Following 2 weeks:
Apply tretinoin every other night - After 6 to 8 weeks of use:
If your skin tolerates the product well, apply the product every night
It is also important to find a balance that is right for you. Your skin may not tolerate the application of tretinoin every day even after weeks of use and you may notice that your skin improves by applying tretinoin every other day instead of daily.
What ingredients can be combined with tretinoin?

You can combine tretinoin with hyaluronic acid to help hydrate and soften your skin.

Use a non-oily moisturizer prior to applying tretinoin to ensure your skin stays moisturized and to avoid irritation.

Always apply sunscreen with SPF 50 since tretinoin will make your skin more sensitive to the sun.
What ingredients should not be combined with tretinoin?

Tretinoin should not be used with other retinoids: retinol, tazarotene, trifarotene, or adapalene.

If you also want to use glycolic acid or salicylic and lactic acid, apply these products on a different day, to avoid irritation.

Be careful when mixing tretinoin with benzoyl peroxide unless they are compounded because they may be too irritating on the skin..
Request an online prescription for tretinoin
Receive a personalized treatment plan.
Start a photo-based virtual consultation with an independent dermatology provider via the Miiskin app.


Start a photo-based virtual consultation to request Tretinoin
References:
1https://www.ncbi.nlm.nih.gov/books/NBK557478/
2https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112391/
3https://www.ncbi.nlm.nih.gov/books/NBK557478/
4https://www.ncbi.nlm.nih.gov/books/NBK557478/
5https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112391/
6https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112391/
7https://jamanetwork.com/journals/jamadermatology/article-abstract/553009
8https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574737/
9https://link.springer.com/article/10.2165/00002512-199506060-00008
10https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225141/
11https://pubmed.ncbi.nlm.nih.gov/16045694/
12https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225141/
13https://rarediseases.info.nih.gov/diseases/517/fetal-retinoid-syndrome
14https://pubmed.ncbi.nlm.nih.gov/26897386/
15https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112391/