Buy Tri-Luma cream with an online prescription
Response time: 1-2 working days
Tri-Luma® cream is a powerful topical prescription cream for individuals with moderate to severe melasma, a common skin condition causing dark patches on the face.
- Board-certified dermatologists
- No expensive medication subscriptions
- Get a Tri-Luma cream prescription for $59
What is Tri-Luma?
Tri-Luma (also referred to as Triluma) is a prescription cream used to treat melasma, a skin condition that causes dark, discolored patches on the face, typically on the cheeks, forehead, and upper lip. It’s often triggered by sun exposure, hormonal changes, or pregnancy.
Tri-Luma combines three active ingredients:
- Hydroquinone (4%) – a skin-lightening agent that reduces pigmentation.
- Tretinoin (0.05%) – a retinoid that promotes skin cell turnover and helps the hydroquinone work more effectively.
- Fluocinolone acetonide (0.01%) – a mild corticosteroid that helps reduce inflammation1.
This triple combination makes Tri-Luma more effective than using any of the ingredients alone. It’s typically used for three to four months, and should be used under the guidance of a dermatologist, as long-term use can lead to side effects like skin thinning, irritation, or rebound pigmentation.
What is Tri-Luma used for?
Tri-Luma is prescribed to reduce dark patches and discoloration on the skin. It’s commonly used for:
Melasma – dark facial patches often caused by sun exposure or hormonal changes
Age spots or sun spots – brown spots from long-term sun exposure
Post-inflammatory hyperpigmentation – dark marks left behind after skin irritation or injury
Uneven skin tone – to help create a more consistent complexion
Freckles – small brown spots from sun exposure and genetics
Dark acne scars – to fade hyperpigmented marks left by acne
Why get online treatment via Miiskin?
First consultation is $59 Medication refills are $30 approx.
Free choice of pharmacy to get the best price.
No subscriptions, order your treatment on-demand.
You can get a customized acne formula.
*The Miiskin-affiliated dermatologists are independent healthcare providers. Miiskin does not interfer with their practice of medicine.
How to buy Triluma cream?
Do you need a prescription to buy Triluma cream?
Yes, Triluma is not available over the counter, so you need a doctor’s prescription to get it.
How to get an online prescription for Triluma cream?
Via Miiskin you can have an online consultation with a board-certified dermatologist. If you haven’t used Triluma cream in the last year and you would like to try it, they will prescribe it, if it is safe and adequate for you.
What is the Triluma cream price?
To get Triluma you need to pay for the virtual consultation which is around $59 and then buy your prescription at a pharmacy. With the Galderma Care Connect Patient Card you can get a 30 gram tube of Tri Luma for $90.
Getting Triluma cream is very simple with Miiskin
- Start a consultation via Miiskin
- Request your prescription for Triluma
- Pick up your Triluma cream at the pharmacy of your choice
Process to getting a prescription for Triluma cream online
Miiskin connects with a virtual dermatologist. They will assess your skin problem, and if they determine that Triluma is appropriate for you, they will issue your prescription, which you can then collect at a pharmacy of your preference.
How is Triluma different from other creams for hyperpigmentation?
Tri-Luma stands out from other topical treatments for hyperpigmentation in several key ways:
- Stronger effect – It’s more potent than most over-the-counter creams because it combines three active ingredients: hydroquinone, tretinoin, and a corticosteroid.
- Combination therapy – While many products contain just one ingredient, Tri-Luma uses a triple-action formula to target pigment, speed up skin cell turnover, and reduce inflammation—all at once.
- Prescription-only – You can’t buy it over the counter; it’s only available with a prescription due to its strength and potential side effects.
- Short-term use – It’s meant for limited use, usually no more than 8 weeks at a time, to avoid skin thinning or irritation.
- Clinically proven – Tri-Luma is the only FDA-approved specifically for melasma2, which gives it a level of validation that many other products don’t have.
Miiskin recommendation
We highly recommend checking with a local pharmacy that carries Tri-Luma cream and accepts the Galderma CAREConnect™ savings card.
You can sign up for the patient program, download the card, and visit nearby pharmacies (such as CVS, Walgreens, or Walmart) to ask about the current price before requesting your prescription. You can also get a GoodRX coupon for Tri-Luma.
This helps ensure you’re not caught off guard if the cost is higher than the expected $90, and allows you to plan accordingly.
Triluma benefits
Tri-Luma offers several key advantages for treating hyperpigmentation, especially melasma:
Fast and noticeable results
Many users see visible improvement in dark spots and skin tone within a few weeks.
Targets multiple causes of pigmentation
Its triple-action formula addresses excess melanin, speeds up skin renewal, and reduces inflammation.
Clinically proven
FDA-approved specifically for melasma, giving it strong clinical backing.
Reduces stubborn pigmentation
Especially effective on patches that haven’t responded well to other treatments.
Improves overall skin tone
Helps even out discoloration for a smoother, more uniform complexion.
Convenient single formula
Combines three powerful ingredients in one cream, simplifying your routine.
Provider & Prescription Information
Miiskin connects patients with independent dermatologists who provide care through their own private practices. Miiskin does not employ dermatologists and does not sell or distribute medications. Any prescriptions issued by the dermatologists can be filled at third-party pharmacies of the patient’s choice.
Warnings and precaution when using Triluma
Tri-Luma contains sulfites, which can cause severe or even life-threatening allergic reactions in people sensitive to them. It also includes hydroquinone, which may lead to a gradual blue-black darkening of the skin with prolonged use.
If you’re pregnant, nursing, or planning to become pregnant, you should not use Tri-Luma. Its safety and effectiveness have not been well studied in individuals with darker skin tones. Because it contains fluocinolone acetonide, a topical steroid, there’s a risk of temporarily suppressing adrenal gland function (HPA axis suppression); stop use and contact your provider if you notice symptoms like fatigue or weakness.
Avoid using products that can dry or irritate your skin, such as scrubs, exfoliants, or harsh cleansers. You should also avoid exposure to direct sunlight, sunlamps, and extreme weather conditions. If you can’t avoid sun exposure, use a broad-spectrum sunscreen with SPF 50 and wear protective clothing3.
Potential side effects of Triluma
- Redness or irritation
- Peeling or dryness
- Burning or stinging sensation
- Skin thinning (with prolonged use)
- Acne breakouts
- Increased sensitivity to sunlight
- Changes in skin color (either lightening too much or uneven pigmentation)4
How to apply Tri-Luma cream
If you’ve been prescribed Tri-Luma, it’s important to use it correctly to maximize results and minimize side effects. This prescription treatment is potent, so following the proper application steps will help you achieve a more even skin tone safely and effectively. Here’s a step-by-step guide:
1. Conduct a patch test
Before using Tri-Luma on larger areas, apply a small amount to a discreet patch of skin and monitor for 24 hours to check for redness, itching, or irritation.
2. Cleanse your skin
Gently wash your face with a mild, soap-free cleanser. Pat your skin dry with a clean towel and wait a few minutes to ensure your skin is completely dry before applying the cream.
3. Apply a thin layer
Using clean fingertips, apply a thin layer of Tri-Luma only to the darkened areas of skin. Massage it in gently and avoid the eyes, mouth, nostrils, and any broken or irritated skin.
4. Use sunscreen with SPF 50
Apply a broad-spectrum sunscreen with SPF 50 every morning, even on cloudy days. Sun exposure can worsen hyperpigmentation and reduce the effectiveness of treatment.
5. Use a moisturizer
Use a gentle, non-comedogenic moisturizer to help prevent dryness, flaking, or irritation that can occur during treatment.
6. Monitor your skin’s response
Watch for signs of excessive redness, peeling, or discomfort. If these occur, stop using the cream and consult your dermatologist for further guidance and evaluation.
7. Schedule follow-up appointments
Regularly check in with your dermatologist, especially if you’re using Tri-Luma through an online consultation, to evaluate your progress and adjust your treatment plan if needed.
Notice
Tri-Luma cream is designed for short-term use, typically for up to 8 weeks, unless otherwise directed by your dermatologist based on your skin’s response and treatment progress.
Start a virtual dermatology consultation to request Tri-Luma cream
Interested in getting a Tri Luma prescription for your melasma?
Consult a Dermatologist →
References:
1 https://www.triluma.com/
2 https://www.galderma.com/us/news/galdermas-tri-luma-cream-only-fda-approved-treatment-melasma-now-available-pharmacies
3 https://www.triluma.com/
4 https://www.triluma.com/
