Request a prescription for hydroquinone online

Response time: 1-2 working days

Board-certified dermatologists
Service available in all 50 states
Choice of generic or customized formulas

Hydroquinone cream for hyperpigmentation displayed with a woman applying skin treatment and a Foothills Pharmacy bottle.

Medically reviewed by:
Dr. Eric Howell
Dermatologist

What is hydroquinone?

Hydroquinone is a skin-lightening ingredient that usually comes in 2% and 4% concentration and it addresses melasma, hyperpigmentation in and dark spots in the skin caused by hormonal changes, sun damage, acne, and skin acne¹.

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Hydroquinone Rx

Your dermatologist will determine whether a generic or compounded treatment is appropriate for your condition and will prescribe a medication tailored to your needs.

Your topical formula may include one or more of the following ingredients:

Hydroquinone
Tretinoin
Tazarotene
Niacinamide
Azelaic acid

Fluocinolone acetonide
Hydrocortisone
Kojic acid
Pracasil

Important Disclaimer: Compounded medications are not reviewed by the FDA for safety or efficacy.

What is hydroquinone cream used for?

Hydroquinone is used to lighten dark spots on the skin.

Melasma

Age spots/sun spots

Post-inflammatory hyperpigmentation

Evening skin tone

Freckles (small, brown spots caused by sun exposure and genetics)

Hyperpigmented acne scars

Hydroquinone brands

Tri-Luma
Triderma
Lustra
Melquin
Solaquin
Melanex

How to buy hydroquinone online?

Do you need a prescription to buy hydroquinone cream?

Yes, hydroquinone creams are not available over-the-counter. You need a doctor’s prescription to buy hydroquinone online

How to get a hydroquinone prescription online?

Start a consultation with an online dermatologist through Miiskin. The dermatologist will review your case and prescribe medication if appropriate, sending it directly to the pharmacy you select. Consultation price is $59 and medication renewals for existing patients are around $30.

Where to buy hydroquinone?

If you are interested in getting a customized hydroquinone formula, select Foothills as your preferred pharmacy. Most Foothills formulas are $48.99.

If you want a standard medication, select any local or online pharmacy.

Important Disclaimer: Compounded medications are not reviewed by the FDA for safety or efficacy.

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How to request a hydroquinone cream prescription online

Select “Start consultation” to sign-up with Miiskin.
Use the consultation form to request hydroquinone.
If medically appropriate, you will receive a prescription from a dermatologist.
Purchase your hydroquinone in the pharmacy of your choice.

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Process to getting a prescription for hydroquinone online
Through an online consultation, you connect with a dermatologist. Upon reviewing your case, if the doctor determines that a cream with hydroquinone is appropriate for you, they will provide a prescription that you can get from the pharmacy of your choosing.

How is hydroquinone different from other creams for hyperpigmentation?

Hydroquinone is a topical skin-lightening agent that is different from other creams for hyperpigmentation in several ways.

Mechanism of action

Hydroquinone works by inhibiting the activity of tyrosinase, which in turn helps lighten dark spots and even out skin tone.

among the most effective lightening agents for the skin

More potency

Hydroquinone is the most potent skin-lightening agents available. It can address stubborn or severe cases of hyperpigmentation.

Can only be used for a limited time

The use of hydroquinone cream is limited to a maximum of 3 months at a time and should only be done under strict medical supervision.

Availability

Hydroquinone cream is only available only with a doctor’s prescription. Some other skin-lightening ingredients are available over-the-counter

Hydroquinone benefits

Inhibits the production of melanin²
Very effective at treating melasma and hyperpigmentation³
Delivers consistent skin lightening results⁴
Offered as combination cream for improved results

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What patients say about Miiskin

Very happy with this service. Quick and easy. With someone with not the greatest insurance and super busy. This was perfect. Got my prescription next day and great advice for my condition.

Marcus Liniarski,
Patient Review →

I had a great experience with Miiskin – I was able to get my prescription very quickly and their app is easy to use. It was very convenient and their team is very responsive. I highly recommend them and will likely use them in the future for other skin issues.

Susie Tse,
Patient Review →

What a technology! I was very impressed by the speed of communication with a doctor using the Miiskin app. Losing my hair has been my biggest concern, but I didn’t have the courage to reveal my bald spot to a doctor in person. Miiskin solved all my issues instantly. I just took a photo in my own room, uploaded it, and wrote about my concerns. That’s it. The best part is that without insurance, the consultation fee was much lower than any health insurance. I submitted my photo at midnight and received a prescription the very next morning. The doctor at Miiskin was very professional and empathetic, which really helped ease my emotional distress. Although I’m just at the beginning stage of my treatment and haven’t seen significant results yet, I feel reassured and supported. I will definitely upload my progress in 3 to 4 months to show my appreciation for the prescription from Miiskin.

Jiyeon Kang,
Patient Review →

My dermatologist was extremely quick, reviewed my consultation request within 2hrs and I had my Rx the next day! The Miiskin team also responds within minutes and are very polite and communicated concisely. I’ll never make a in person appointment again after experiencing this outstanding and affordable telehealth service!

Dion H,
Patient Review →

Quick response from the dermatologist — I wanted a fast turnaround for a skin concern that would be more immediate than going through health insurance, making an appointment, traveling to the doctor.

Timothy C.
Patient Review →

Side effects and Warnings

Potential side effects of hydroquinone cream

Dryness, flaking, itching, or a sensation of burning on the skin
Reduced thickness of the skin, increasing susceptibility to bruising
Alteration in the skin’s natural color, resulting in darkening
Scaling around the mouth area
Formation of blisters, crusts, or flakes on the skin
Appearance of redness, irritation, or the emergence of rashes
Lightening of the usual skin hue
Redness, tenderness, or extensive peeling of the skin⁵

Warning and precaution when using hydroquinone

You should only use hydroquinone under medical supervision. Pregnant and nursing women should not use hydroquinone as it is not safe for the unborn baby. Individuals taking any type of medications should always inform their healthcare provider before using it.

Hydroquinone can increase skin sensitivity to the sun, so protect your skin with sunscreen and avoid excessive sun exposure. Begin with a lower concentration if you are new to hydroquinone, and use it once a day in the evening.

Discontinue use if severe irritation occurs, and avoid contact with eyes and mucous membranes. Regular follow-ups with a dermatologist can help monitor progress and adjust treatment as needed.

How to use hydroquinone cream?

According to Dr. Eric Howell, board-certified dermatologist, if you have been prescribed with hydroquinone, this is how you should use it.

1. Conduct a patch test

Always conduct a patch test for hydroquinone before widespread use to identify potential skin reactions. Apply a small amount to a small skin area and monitor for any adverse reactions, such as redness or irritation, over the next 24 hours.

2. Cleanse your skin

Begin by cleansing your skin gently using a mild, soap-free cleanser. Afterward, pat your skin dry with a clean towel, ensuring it’s completely dry before applying hydroquinone.

3. Apply a thin layer

Apply a thin layer of hydroquinone cream or gel to the desired treatment areas using clean fingertips. Massage the product into your skin evenly, but avoid the eye, mouth, and mucous membrane areas.

4. Use sunscreen with SPF 50

It is recommended toapply a broad-spectrum sunscreen with a SPF 50 daily, particularly in the morning. UV exposure can exacerbate hyperpigmentation and counteract the efficacy and benefits of hydroquinone cream.

5. Use a moisturizer

6. Monitor your skin’s response

Monitor your skin’s response to hydroquinone closely. If you experience excessive irritation, redness, or any adverse reactions, discontinue use and seek guidance from your healthcare provider.

7. Schedule follow-up appointments

Schedule follow-up appointments with your online dermatologist to assess your progress, address any concerns, and make any necessary adjustments to your treatment plan.

Notice

Keep in mind that hydroquinone should not be used long-term. It is generally recommended to discontinue use after a maximum of 4 months, whether it has achieved the desired results or not. Discuss treatment plan for dark spot recurrence with your dermatologist.

Provider & Prescription Information

Miiskin connects patients with independent dermatologists who provide care through their private practices. Compounded prescriptions can be ordered via Miiskin and are dispensed by Foothills pharmacy. Generic prescriptions can be filled at any local or online pharmacy.

Got more questions about getting an hydroquinone prescription?

How does hydroquinone work?

It works by blocking an enzyme called tyrosinase, which plays a key role in melanin production. By reducing melanin, hydroquinone gradually lightens darkened areas of skin.

How can I get a hydroquinone prescription online?

You can have an online consultation with a board-certified dermatologist through Miiskin. If hydroquinone is appropriate for you, the prescription can be issued digitally.

Where can I purchase hydroquinone cream?

With a valid prescription, hydroquinone can be filled at a local pharmacy. If you wish a compounded medication, simply choose Foothills as your preferred pharmacy. Your dermatologist will issue a prescription with a customized formula designed for you. Most Foothills formulas are $48.99, with a few advanced formulas being priced at $58.99.

How should I use hydroquinone cream?

Apply a thin layer only to the dark spots once or twice daily, following your dermatologist’s instructions. Wash your hands after application and avoid spreading it onto surrounding normal skin.

How long does hydroquinone take to show results?

Many people start to see improvement within 4–8 weeks of regular use, though results can vary depending on the type and severity of pigmentation.

Can hydroquinone be used long term?

No. Hydroquinone is generally recommended for short-term use, usually up to 3–6 months. Longer use may increase the risk of side effects such as ochronosis.

Is sunscreen required while using hydroquinone?

Yes. Daily sunscreen is essential because hydroquinone increases sun sensitivity, and UV exposure can worsen pigmentation.

Is hydroquinone suitable for all skin types?

Hydroquinone can be effective for many skin types, but individuals with darker skin tones may have a higher risk of side effects. Dermatologist supervision is strongly recommended.

Can hydroquinone be used during pregnancy or breastfeeding?

Hydroquinone is typically not recommended during pregnancy or breastfeeding, as its safety has not been fully established. Always consult your healthcare provider first.

What’s the difference between lower-strength and prescription hydroquinone?

Lower-strength hydroquinone products may be available over the counter in some regions, while prescription versions are stronger and often more effective for persistent discoloration.

Can hydroquinone be used with other skincare products?

Yes, but it should not be combined with harsh exfoliants or irritating products unless advised by a dermatologist. It’s often paired with tretinoin and a mild steroid to enhance results.

What should I do if I miss an application?

Apply the cream at your next scheduled time. Do not apply extra product to make up for a missed dose.

References:
¹https://www.ncbi.nlm.nih.gov/books/NBK539693/
²https://www.ncbi.nlm.nih.gov/books/NBK539693/
³https://pubmed.ncbi.nlm.nih.gov/12709008/
⁴https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122278/
⁵https://my.clevelandclinic.org/health/drugs/19764-hydroquinone-skin-cream-gel-emulsion-lotion-or-solution