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Home / Tretinoin prescription online

Get a tretinoin prescription online

Time  Response time: 1-2 working days

  • Board-certified dermatologists
  • No medication susbcription
  • Get a customized Foothills formula from $48.99
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Miiskin platform displaying facial photo upload for an online dermatology assessment, shown with Tretinoin 0.05% prescription cream and Foothills skincare product

Table of Content:
What is tretinoin? | A seamless experience | How to get tretinoin? | Benefits | Uses | How does it work? | What patients say | Strengths | Precautions | The tretinoin purge | How to use it? | Tretinoin and other ingredients |FAQ

Content last updated: October 2025


Dermatologist  Dr. Anna Chacon
Medically reviewed by:
Dr. Anna Chacon
Dermatologist
treating acne with tretinoin

What is tretinoin?

Tretinoin (generic version of Retin-A) is a topical prescription medication  widely used by dermatologists to treat acne, hyperpigmentation, wrinkles and sun damage1.

Tretinoin works by accelerating the lifecycle of skin cells and boosting new collagen formation. It belongs to a family of synthetic and natural compounds called retinoids that are derived from Vitamin A2.

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A seamless teledermatology + pharmacy experience

Miiskin has now partnered with Foothills Pharmacy, a leading compounding pharmacy, to make prescription skin care effortless.

Now, when your dermatologist prescribes treatment via Miiskin, you can choose Foothills as your pharmacy and order your medication via the Miiskin platform. They will send a payment link and after payment is completed, your medication will be delivered for free with a UPS 2-day shipping.

Important Disclaimer: Compounded medications are not reviewed by the FDA for safety or efficacy.

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anti-aging treatment with miiskin

How to get tretinoin online?

How to get a tretinoin prescription?

To get a tretinoin prescription, you can have an online consultation with a board-certified dermatologist through Miiskin.

How much does it cost to get a tretinoin prescription online?

The consultation fee with an online dermatologist via Miiskin is around $59 for first-time patients and $39 for prescription renewals.

How to get a tretinoin then?

If you are interested in a customized tretinoin formula, select Foothills as your preferred pharmacy. Most Foothills formulas are just $48.99 and includes free delivery. If you want a generic tretinoin tube, you can select any local or online pharmacy.

how to get tretinoin prescription
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Benefits of tretinoin

a dermatological app for patients

Stimulates collagen for firmer skin

Reduces wrinkles

Reduces fine lines and wrinkles

Improves skin texture

Smooths skin texture and tone

Reduces the appearance of dark spots

Fades dark spots and discoloration

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Unclogs pores and reduces breakouts

Has anti-inflammatory effects

Prevents future acne formation

What is tretinoin cream or gel used for?

Tretinoin is approved by the FDA for the treatment of:

Acne Treatment

Acne and acne scars

Facial Wrinkles Treatment

Facial wrinkles

Skin roughness treatment

Skin roughness

Hyperpigmentation Treatment

Hyperpigmentation3

Brand names of tretinoin gels or creams

  • Retin – A
  • Altreno
  • Atralin
  • Avita
  • Refissa
  • Renova
  • Tretin – X
  • Retin – A micro
Tretinoin Gels Brand names

Get an online tretinoin prescription via Miiskin

  1. Select “Start consultation” to sign up.
  2. Fill out the consultation form and take photos of your skin.
  3. An independent dermatologist will prescribe tretinoin to you, if medically appropriate.
  4. Buy tretinoin affordably from the pharmacy of your choice.
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Buy prescription medicine

How to get a prescription for tretinoin?
Miiskin connects with a board-certified, online dermatologist. After reviewing your case, if the dermatologist determines that tretinoin is safe and appropriate for you, they will issue your prescription to the pharmacy of your choosing.

Tretinoin explained

How does tretinoin work?

Tretinoin stimulates cell renewal in the epidermis, enhancing the cell layer, reducing pigmentation and normalizing sun-damaged cells4.

Tretinoin also works in the dermis promoting the production of collagen and elastin thickening the dermal layer and making the skin appear more plump5.

According to multiple research, tretinoin gels and creams are a safe and effective therapeutic modality for the long-term treatment of acne and photoaging.6 78

workflow management between primary care and dermatologists

What patients say about Miiskin

Very happy with this service. Quick and easy. With someone with not the greatest insurance and super busy. This was perfect. Got my prescription next day and great advice for my condition.

Marcus Liniarski,
Patient Review →

10 of 10stars

I had a great experience with Miiskin – I was able to get my prescription very quickly and their app is easy to use. It was very convenient and their team is very responsive. I highly recommend them and will likely use them in the future for other skin issues.

Susie Tse,
Patient Review →

10 of 10stars

What a technology! I was very impressed by the speed of communication with a doctor using the Miiskin app. Losing my hair has been my biggest concern, but I didn’t have the courage to reveal my bald spot to a doctor in person. Miiskin solved all my issues instantly. I just took a photo in my own room, uploaded it, and wrote about my concerns. That’s it. The best part is that without insurance, the consultation fee was much lower than any health insurance. I submitted my photo at midnight and received a prescription the very next morning. The doctor at Miiskin was very professional and empathetic, which really helped ease my emotional distress. Although I’m just at the beginning stage of my treatment and haven’t seen significant results yet, I feel reassured and supported. I will definitely upload my progress in 3 to 4 months to show my appreciation for the prescription from Miiskin.

Jiyeon Kang,
Patient Review →

10 of 10stars

My dermatologist was extremely quick, reviewed my consultation request within 2hrs and I had my Rx the next day! The Miiskin team also responds within minutes and are very polite and communicated concisely. I’ll never make a in person appointment again after experiencing this outstanding and affordable telehealth service!

Dion H,
Patient Review →

10 of 10stars

Quick response from the dermatologist — I wanted a fast turnaround for a skin concern that would be more immediate than going through health insurance, making an appointment, traveling to the doctor.

Timothy C.
Patient Review →

10 of 10stars

I’d been dealing with psoriasis for a while and couldn’t believe it when the dermatologist I was referred to gave me an appointment six months out. That just wasn’t going to work. I looked online, found a couple of options, and after doing a bit of research, decided to move forward with a digital dermatology appointment through Miiskin – and I’m so glad I did. What stood out immediately was how fast everything moved. I didn’t have to wait days for a response, and I was able to send in photos, get a diagnosis, and pick up a prescription – all in the same day. It was seamless. The communication has been great too – I’m still able to check in and share follow-up pictures as my treatment progresses. I was nervous at first. I’d never done a telehealth visit before and wasn’t sure what to expect. But this experience changed that completely. It was easy to use, efficient, and honestly better than past in-person appointments I’ve had. I didn’t feel rushed – I felt heard. I’d absolutely recommend digital dermatology to anyone. In fact, I’ve already told my grandson about it. For someone like me, who has a hard time getting around, this has been a game-changer. It’s convenient, reliable, and most importantly – it works.

Yvonne Peters, Hayward, CA
Patient Review →

10 of 10stars

Most common tretinoin strengths prescribed

Tretinoin Cream 0.025%

Tretinoin cream at 0.025% concentration is a gentler option, often recommended for patients new to tretinoin or those with sensitive skin. Its lower strength allows for a gradual introduction to tretinoin, reducing the chance of irritation. It’s commonly used for mild concerns such as fine lines, uneven skin tone, and mild acne.

Tretinoin Cream 0.05%

Tretinoin cream 0.05% works faster and produces more visible results than the 0.025% cream. It’s a moderate-strength option suitable for addressing more prominent signs of aging, moderate acne, and persistent hyperpigmentation. Although it carries a higher risk of side effects like dryness, following your doctor’s guidance can help manage any reactions and maximize its effectiveness.

Tretinoin Cream 0.1%

Tretinoin cream 0.1% is considered high-strength and is typically reserved for more intense treatment needs. It is often recommended for individuals with more severe skin concerns, such as deep wrinkles, pronounced signs of aging, or stubborn acne that requires stronger intervention.

tretinoin strengths creams and gels
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Warnings, side effects and purging

Warning and precautions when using tretinoin creams or gels

This medication should only be used under medical supervision and it is advised that women use effective contraception when using tretinoin.

Tretinoin is considered teratogenic, and therefore it cannot be used by women who want to become pregnant, are pregnant, or are breastfeeding because it may cause serious harm to the fetus13 14. 

Tretinoin is likely to make your skin more sensitive to sunlight so you should apply sunscreen with SPF 50 factor every morning while using this product and reapply every two hours when outdoors.

Tretinoin may cause skin irritation when you first start using it, follow the precise instructions of your healthcare provider to minimize unwanted side effects.
Do not combine tretinoin with other acne or pigmentation medications, unless indicated by your doctor. 

Side effects of tretinoin

  • Redness
  • Peeling
  • Itching
  • Burning/Stinging
  • Dryness15

What is the tretinoin purge?

The tretinoin purge (also known as tretinoin uglies) is a very common skin reaction that occurs when a patient uses tretinoin for the first time.

Learn more about the tretinoin purge →

How to use Tretinoin

How to get started once tretinoin is prescribed?

You should always follow the precise instructions of your healthcare provider, because your treatment plan will depend on your skin condition and your skin type. However, as a general rule, if you have never used tretinoin, here is a good way to start.

  • First 2 to 4 weeks:
    Apply tretinoin .025% two nights per week in the evenings
  • Following 2 weeks:
    Apply tretinoin every other night
  • After 6 to 8 weeks of use:
    If your skin tolerates the product well, apply the product every night

It is also important to find a balance that is right for you. Your skin may not tolerate the application of tretinoin every day even after weeks of use and you may notice that your skin improves by applying tretinoin every other day instead of daily.

How to use Tretinoin correctly

Watch this 2-minute video where doctor Anna Chacon, board-certified dermatologist in the Miiskin network, explains how to use tretinoin the proper way to minimize the potential of irritation.

Click to read video transcript

How to Use Tretinoin
– Start with a gentle cleanser.
– Wash your face with lukewarm water and pat dry with a soft towel.
– Always make sure your skin is completely dry before applying tretinoin — wait about 15 to 20 minutes. This helps minimize irritation.
– Before applying tretinoin, always start with a gentle, non-comedogenic moisturizer. This helps protect your skin barrier and reduces dryness and peeling.
– Next, squeeze out a pea-sized amount — that’s really all you need for your entire face. Dot the tretinoin across your forehead, both cheeks, nose, and chin. Then gently spread it evenly over your entire face.
– Avoid the corners of your mouth, the creases around your nose, and the delicate skin around your eyes — these areas are more prone to irritation.
– Apply an additional layer of moisturizer across the face and neck. This is optional but recommended, especially if you have sensitive skin. You can also use a hyaluronic serum instead of a moisturizing cream.
– Remember, tretinoin takes time to work. You may not see results for several weeks, but consistency is key.
– Tretinoin requires a prescription from a dermatologist. If you are interested in getting a personalized tretinoin formula — with up to three additional ingredients for your skin — I am here to help.

Click the link to start your consultation today.

What ingredients can be safely
combined with tretinoin?

IncludedSunscreen SPF 50

IncludedHyaluronic acid

IncludedNon-greasy moisturizer

IncludedAzelaic acid

IncludedNiacinamide

IncludedPeptides

IncludedCeramides

What ingredients should not be combined with tretinoin?

  • Benzoyl peroxide* 
  • Glycolic acid*
  • Lactic acid*
  • Salicylic acid*
  • Retinol
  • Tazarotene
  • Trifarotene
  • Adapalene

*Unless instructed by a dermatologist

Provider & Prescription Information

Miiskin connects patients with independent dermatologists who provide care through their private practices. Compounded prescriptions can be ordered via Miiskin and are dispensed by Foothills pharmacy. Standard medications can be issued for any local pharmacy.

Got more questions about getting a tretinoin (Retin-A) prescription?

What is best a customized tretinoin formula or a generic tretinoin tube?

Both options can be effective, but the better choice depends on your skin’s needs. A generic tretinoin tube is a simple, FDA-approved medication with a fixed strength, making it reliable and affordable. A customized tretinoin formula, on the other hand, can combine tretinoin with other ingredients like niacinamide, azelaic acid, or topical spironolactone to target multiple concerns at once. Custom formulas may offer a more tailored experience, especially if you struggle with irritation or have several skin issues to address, while generic tretinoin is ideal if you want a straightforward, proven treatment.

How much are customized tretinoin-based formulas via Miiskin?

Most customized Foothills formulas are $48.99 for a 30-gram tube, a few advanced formulas are priced at $58.99. This price includes a 2-day UPS shipping.

Can you buy tretinoin over the counter?

In the United States, tretinoin is a prescription-only medication and cannot be purchased over the counter. Miiskin provides a convenient way for users to access tretinoin online by connecting them with licensed U.S. healthcare providers for a quick virtual consultation. If prescribed, the medication is then dispensed and shipped directly to the patient, allowing users to safely and easily obtain tretinoin without an in-person doctor visit.

How to buy tretinoin online?

In the United States, tretinoin requires a prescription and cannot be bought over the counter. Through Miiskin, users can conveniently obtain tretinoin online by completing a short digital consultation with an independent board-certified dermatologist. After the dermatologist reviews the user’s skin concerns and determines tretinoin is appropriate, the prescription is sent to a partner pharmacy, and the medication is shipped directly to the patient’s home, making the process safe, legitimate, and convenient.

What is the price of getting a tretinoin prescription via Miiskin?

A consultation to get a tretinoin prescription costs about US $59 for new patients, and around US $39 for prescription refills.

How long will it take to get the prescription for my tretinoin?

Most users receive their tretinoin prescription within 24 hours, but you need to wait up to 2 business days after submitting a online consultation.

Is Botox or tretinoin better?

Botox and tretinoin work in completely different ways, so “better” depends on your goals. Botox temporarily relaxes the muscles that cause expression lines—like frown lines or crow’s feet—making it best for smoothing existing dynamic wrinkles. Tretinoin, on the other hand, is a prescription retinoid that improves skin texture, stimulates collagen production, and helps prevent fine lines from forming, but results appear gradually over months. Many dermatologists actually recommend using both together: tretinoin for long-term skin health and prevention, and Botox for immediate, targeted wrinkle reduction.

Can I use tretinoin long-term?

Yes — tretinoin can be used long-term under the guidance of a healthcare professional. In fact, many dermatologists recommend ongoing use to maintain results for acne control, skin texture improvement, and anti-aging benefits.

That said, tretinoin should be used consistently but carefully: most people tolerate it well once their skin adjusts, but it can cause dryness, peeling, or irritation, especially in the early weeks. Using moisturizer, sunscreen, and following the prescribed strength and frequency help minimize side effects.

Tretinoin virtual consultation

Start a virtual consultation to request Tretinoin

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Teledermatology Clinic Online Want a customized tretinoin formula?
Consult a Dermatologist →

References:
1https://www.ncbi.nlm.nih.gov/books/NBK557478/
2https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112391/
3https://www.ncbi.nlm.nih.gov/books/NBK557478/
4https://www.ncbi.nlm.nih.gov/books/NBK557478/
5https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112391/
6https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112391/
7https://jamanetwork.com/journals/jamadermatology/article-abstract/553009
8https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574737/
9https://link.springer.com/article/10.2165/00002512-199506060-00008
10https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225141/
11https://pubmed.ncbi.nlm.nih.gov/16045694/
12https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225141/
13https://rarediseases.info.nih.gov/diseases/517/fetal-retinoid-syndrome
14https://pubmed.ncbi.nlm.nih.gov/26897386/
15https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9112391/

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Miiskin is an online dermatology consultations platform that connects patients with independent dermatologists.

All consultations are provided by independent online dermatologists on a cash-pay-only basis. Miiskin does not practice medicine or pharmacy. Prescriptions, if medically appropriate, are sent to third-party pharmacies, which are paid directly for any medication. Medication images on the website are for illustrative purposes only and images of people are not actual patients. Medical information on miiskin.com is for informational purposes and not medical advice. Consult a healthcare provider for any concerns.

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