Get a customized topical spironolactone formula
Response time: 1-2 working days
- Board-certified dermatologists
- Customized formula with up to 5 ingredients
- No medication subscriptions


What is topical spironolactone?
Spironolactone is an ingredient that has FDA-approved uses in its oral form. In some cases, prescribers may request that pharmacies prepare topical formulations as compounded medications.
Compounded medications, including topical spironolactone, are not reviewed by the FDA for safety or efficacy. These medications are prepared by pharmacies in response to a licensed prescriber’s determination of individual patient needs.
Professional care, personalized formulas
Miiskin works with board-certified dermatologists who may prescribe compounded skincare treatments tailored to each patient’s needs.
Discussions during your consultation may include ingredient options such as tretinoin, niacinamide, or others — depending on your provider’s recommendations.
No subscriptions. No hidden costs. You only pay when you need treatment.
Important Disclaimer: Compounded medications are not reviewed by the FDA for safety or efficacy.

How to get a topical spironolactone prescription?
Do you need a prescription for topical spironolactone?
Yes. Topical spironolactone is only available as a compounded medication, which means it must be prescribed by a licensed healthcare provider. Compounded medications are prepared by pharmacies to meet the individual needs of a patient, based on a prescriber’s clinical judgment.
How can you get a prescription for a compounded formula that may include spironolactone?
Through Miiskin, you can request an online consultation with a dermatologist. The consultation fee is around $59 for new patients and $30 for medication renewals for existing patients. If the dermatologist determines that a compounded medication is appropriate for your situation, they may write a prescription.
Where can you get compounded medications that may include spironolactone?
If prescribed, your medication will be prepared by a licensed compounding pharmacy and shipped to you.
Is topical spironolactone FDA-approved?
No. Topical spironolactone is not FDA-approved. Compounded medications are not reviewed by the FDA for safety or efficacy.

Request a personalized formula with topical spironolactone via Miiskin
- Select “Start consultation” to sign up.
- Fill out the consultation form and take photos of your skin.
- An independent dermatologist will prescribe a personalized formula with topical spironolactone to you, if medically appropriate.
- Buy topical spironolactone online from a compounding pharmacy


Process to getting a prescription for acne
Through Miiskin, you get in touch with a dermatologist using an online dermatology consultation. The dermatologist will review your case and will write you a prescription for topical spironolactone cream if it is suitable for you. Then you can pick it up at the pharmacy.
Important information about compounded topical medications
Compounded medications, including those that may contain spironolactone or tretinoin, are not FDA-approved. This means they have not been reviewed by the FDA for safety or efficacy, and there is no FDA-approved labeling that describes side effects.
Some patients who use topical skincare preparations containing active ingredients such as tretinoin or spironolactone have reported experiencing skin reactions like dryness, redness, irritation, or itching. Because compounded medications are customized, potential effects can vary depending on the formulation and the individual.
If you have questions about potential risks, or if you experience any unexpected reactions, it’s important to discuss them directly with your prescribing dermatologist or pharmacist.


How to use your customized formula?
You should always follow the instructions of your healthcare provider, however, as a general rule, if you have never used a compounded formula, here is a good way to start.
- Cleanse:
Wash with a gentle cleanser and dry your skin. - Moisturize:
After the medication absorbs, use a gentle moisturizer to reduce dryness. - Apply medication:
Apply a thin layer of the formula on dry skin, at nighttime avoiding sensitive areas like eyes and corners of the mouth. - Sun protection:
Apply sunscreen every morning.
It is also important to find a balance that is right for you. Your skin may not tolerate the application of your customized formula every day straight away. Apply it every other day instead of daily in the beginning if you experience irritation, once your skin is used to it, apply daily.
Provider & Prescription Information
Miiskin connects patients with independent dermatologists who provide care through their own private practices. Miiskin does not employ dermatologists and does not sell or distribute medications. Any prescriptions issued by the dermatologists can be filled at third-party pharmacies of the patient’s choice.
References:
1https://pmc.ncbi.nlm.nih.gov/articles/PMC8247934/
2https://pmc.ncbi.nlm.nih.gov/articles/PMC8247934/
3https://pmc.ncbi.nlm.nih.gov/articles/PMC5574737/


Want a customized prescription for your skin?