Seysara® side effects, benefits and dosing for acne

Table of Content:
What is it and how does it work? | Advantages | Side effects | Who can take Seysara? | Dosage | How to get it? | Price | Patient coupon | Seysara vs doxycycline

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In the pursuit of clearer and healthier skin, Seysara antibiotic has emerged as a strong player in the treatment of acne. As individuals seek effective solutions to manage acne, understanding the potential side effects and the benefits of Seysara, along with the appropriate dosing, is important so you can discuss with your online dermatologist if this medicine is adequate for you.

In this article we explain the different aspects of Seysara, shedding light on its impact, advantages, and recommended dose for those  struggling with acne.

What is the price of Seysara?

Seysara is an expensive medication if you do not have a health insurance that covers it. If you download a Patient Savings Coupon from the manufacturer you may be able to get it at a retail price of $175 for 30 tablets, and even less if it’s Admiral Advantage pharmacy

How to get acne treatment?

If you are interested in trying Seysara for acne or any other acne medication, you can have a consultation with a board-certified dermatologist via Miiskin for $59. Existing patients pay $39.

Seysara antibiotic: what is it and how does it work?

Seysara is a fairly new tetracycline antibiotic approved by the FDA for the treatment facial and truncal moderate to severe acne in people aged 9 years and older¹. It works by targeting and reducing the amount of acne-causing bacteria on the skin^2. 

Sarecycline, the active ingredient in Seysara,  is highly effective against the bacteria that causes acne. Since it mostly targets acne-causing bacteria and is not effective against some other types, it is less likely to cause antibiotic resistance and has fewer side effects than other antibiotics³. 

Seysara side-effects

The side effects of the Seysara antibiotic are usually milder than other tetracycline antibiotics. They tend to be temporary and may go away with time as the body adjusts to the medication. 

Some of the common side effects of Seysara include:

• Nausea
• Vomiting
• Diarrhea
• Headaches
• Tiredness⁴ 

Who can take the Seysara?

Patients over 9 years old with facial and truncal moderate to severe acne. 

Who cannot take Seysara?

Patients with hypersensitivity to tetracyclines should not take Sarecycline¹⁰ 

Women who are pregnant or breastfeeding should not take sarecycline because it can affect the development of teeth and bones in the unborn baby. Sarecycline passes into the breast milk and may affect the bone and tooth development in the nursing baby^11. 

Tell your healthcare provider if you are pregnant or if you become pregnant.

Sarecycline is not approved for the use in children under 9 years of age. This medicine may cause permanent yellow or gray discoloration of children’s teeth.

Seysara dosage

You should always follow the directions given by your healthcare provider, but as a rule of thumb, Seysara tablets should be taken once a day for no longer than 12 weeks.

Seysara comes in three different formulations: tablets with 60 mg, 100 mg and 150 mg and the prescribed dosage is based on individual body weight: 

• For patients who weight 33 to 54 kg (73 to 120 lb) → 60 mg
• For patients who weight 55 to 84 kg (121 to 186 lb) → 100 mg
• For patients who weight 85 to 136 kg (187 to 300 lb) → 150 mg¹²

Does Seysara cause weight gain?

Weight gain is not listed as a common or rare side effect of Seysara tablets in the prescribing information approved by the Food and Drug Administration^13.

Seysara vs doxycycline

Sarecycline and doxycycline are both oral antibiotics used to treat acne, but they differ in a few important ways.

Firstly, sarecycline is a newer antibiotic that was specifically developed and approved by FDA for the treatment of  moderate to severe acne. On the other hand, doxycycline, is an older antibiotic that has been widely used for the treatment of bacterial infections and acne.

Sarecycline is a narrow-spectrum antibiotic, which means it specifically targets acne-causing bacteria. In contrast, doxycycline is a broad-spectrum antibiotic, which means it can target a wider range of bacteria. This broader spectrum of activity means that doxycycline increases the risk of side effects and the development of antibiotic resistance. 

Thirdly, doxycycline causes sun sensitivity, while sarecycline is less likely to have this side effect. 

Overall, both sarecycline and doxycycline are effective acne treatments, but the choice of antibiotic may depend on the severity and type of acne, as well as patient factors such as age, medical history, and other medications being taken. 

A healthcare provider is the best person to determine which treatment (antibiotics or retinoids) may be most appropriate for your type of acne.

Article References:
https://www.fda.gov/drugs/drug-approvals-and-databases/drug-trials-snapshot-seysara
https://seysara.com/starting-seysara/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9220064/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC99026/
https://jddonline.com/articles/article-oral-tetracyclines-and-acne-a-systematic-review-for-dermatologists-S1545961620S00s6X
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840093/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937166/
https://www.seysara-hcp.com/#tolerability-section
https://www.ncbi.nlm.nih.gov/books/NBK556599/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6090842/
https://static.almirall.us/pdf/Seysara_uspi_final_Jun2020.pdf
https://seysara.com/patient-savings/